High-Capacity Cation-Exchange Column for the Separation of Polar Amines
The Thermo Scientific Dionex IonPac™ CS19 carboxylate-functionalized cation-exchange column is tailored for the separation of six common cations, small polar amines (including alkanolamines and methylamines) and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines) using simple aqueous eluents and elevated temperatures. The Dionex IonPac CS19 column is ideal for use with RFIC™ systems for automatic methanesulfonic acid eluent generation.
- For analysis of amines including alkanolamine and methylamines in diverse sample matrices
- For analysis of moderately-hydrophobic amines including biogenic amines, alkyl diamines, and polyvalent amines
- Optimized for simple acidic gradient separations with minimal baseline shift
- Ideal Reagent-Free™ electrolytic suppression with the Thermo Scientific Dionex CSRS™ 300 Cation Self-Regenerating Suppressor™
- Compatible with organic solvents, acetonitrile, and acetone up to 100%, excluding alcohols
- High capacity allows routine analysis of high-ionic-strength samples
The Dionex IonPac CS19 cation-exchange column supports isocratic and gradient separations of polar amines, moderately hydrophobic amines, and polyvalent cations using suppressed conductivity detection. The Dionex IonPac CS19 column has a higher capacity than the Thermo Scientific Dionex IonPac CS18 column. This allows the analysis of widely disparate peak pairs and high-ionic strength matrices with less overloading of the column.
The Dionex IonPac CS19 column is targeted for analysis of power plant waters treated with ammonium, morpholine, or ethanolamine; as well as chemical additives; chemical process solutions; scrubber solutions; personal care products; and food samples.
The Dionex IonPac CS19 column is available in 4 × 250 mm, 2 × 250 mm, and 0.4 × 250 mm formats.The microbore and capillary formats require less eluent thereby reducing operating costs.
| Thermo Scientific Dionex IonPac™ CS19 Cation-Exchange Column Specifications |
|---|
| Dimensions: | Dionex IonPac CS19 Analytical Column: 4 × 250 mm Dionex IonPac CG19 Guard Column: 4 × 50 mm Dionex IonPac CS19 Analytical Column: 2 × 250 mm Dionex IonPac CG19 Guard Column: 2 × 50 mm Dionex IonPac CS19 Capillary Column: 0.4 × 250 mm Dionex IonPac CG19 Capillary Guard Column: 0.4 × 50 mm |
| Maximum Operating Pressure: | 3000 psi (Standard, microbore and capillary) |
| Mobile Phase Compatibility: | Acidic eluents, 0–100% HPLC solvents, excluding alcohols |
| Substrate Characteristics: | Bead Diameter: 5.5 µm Crosslinking (%DVB): 55% |
| Functional Group Characteristics: | Ion-Exchange Group: Grafted carboxylic acid Surface Characteristics: Medium hydrophobic |
| Capacity: | 2410 µeq (4 × 250 mm analytical column) 46 µeq (4 × 50 mm guard column) 600 µeq (2 × 250 mm analytical column) 11 µeq (2 × 50 mm guard column) 24 µeq (0.4 × 250 mm capillary column) 0.5 µeq (0.4 × 50 mm capillary guard column) |
| Column Construction: | PEEK™ with 10-32 threaded ferrule style end fittings. All components are nonmetallic. (4 mm and 2 mm columns) |

Isocratic separation of the six common cations using the Thermo Scientific Dionex IonPac* CS19 column.

Determination of common cations plus ammonium and ethylamines using the Dionex IonPac CS19 column.

Separation of common inorganic cations and ethanolamines using the Dionex IonPac CS19 column.

Separation of Group I and II inorganic cations plus ammonium using the Dionex IonPac CS19 column.

Separation of methylamines and the common inorganic cations using the Dionex IonPac CS19 column.
The Dionex IonPac CS19 column can easily separate biogenic amines and the common cations
using an aqueous eluent without organic solvent.

Gradient separation of the six common cations, methylamines and imidazoles using the Dionex IonPac CS19 column.

Gradient separation of the six common cations plus paraquat and diquat using the Dionex IonPac CS19 column.
| Analytical Columns |
| IonPac CS19 Capillary Column (0.4 x 250 mm) |
076024 |
| IonPac CS19 Analytical Column (4 x 250 mm) |
076026 |
| IonPac CS19 Analytical Column (2 x 250 mm) |
076028 |
| Guard Columns |
| IonPac CG19 Capillary Guard Column (0.4 x 50 mm) |
076025 |
| IonPac CG19 Guard Column (4 x 50 mm) |
076027 |
| IonPac CG19 Guard Column (2 x 50 mm) |
076029 |