Analytical Performance for the DMPK Lab

Drug metabolism and pharmacokinetics (DMPK) require the rigorous qualitative and quantitative treatment of numerous in-vitro and in-vivo samples. Dionex partners with DMPK scientists worldwide to offer a wide array of solutions based on flexible, accurate and reliable IC and HPLC systems. These system solutions enable the DMPK scientist to accelerate their workflow without compromise.

Our capabilities also allow scientists to work with minute amounts of biological sample, enabling analyses that previously were not possible.

UltiMate RSLC-based Solutions Provide Unsurpassed Speed

Samples, samples, samples. Drug metabolism and pharmacokinetic (DMPK) studies quickly add up with more samples than time to analyze them. Dionex RSLC system solutions offer both high resolution and high speed. Designed for small particle columns, chromatographic methods can be optimized for the shortest analysis times possible while maintaining high resolution.

The UltiMate^® x2 Dual system provides the throughput of two HPLC systems while occupying the bench space of only one. Configurable in parallel or tandem arrangements, the x2 Dual is the answer for demanding sample loads found in pre-clinical development.

Sensitivity

State-of–the-art in liquid chromatography demands speed, selectivity and sensitivity. The RSLC line of system solutions offers both variable wavelength and diode array detectors specifically designed for the fast UHPLC separations. With scan rates of up to 100Hz, these detection systems can produce data points and/or scans sufficient to produce accurate and precise quantitation.