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Dietary and Herbal Supplements

Nutritional supplements replace vitamins we lose in normal metabolic function or are missing from our diet. Our bodies are dependent on a number of essential vitamins for a variety of biological processes, such as a healthy immune system, proper metabolic function, and regeneration of cells. Among the essential vitamins are A, C, D, E, K, and the Vitamin B family, which includes thiamin, riboflavin, niacin, pantothenic acid, biotin, folate, pyridoxine (B-6), and cyanocobalamin (B-12).

There are other essential nutrients that the body requires that can be deficient due to several reasons, hence the reason for dietary supplements. For example, water-soluble vitamins are not stored in the body, and must be replenished regularly. These vitamins include the B complex group and vitamin C. Also, these vitamins are easily destroyed or converted to less useful complexes during food preparation or storage. Another group of vitamins that can be difficult to obtain in sufficient quantities are fat-soluble vitamins, which include vitamins A, D, E, and K. Mineral compounds, such as zinc, iron, magnesium, and calcium also fall in this latter category.

Herbal supplements are a rapidly growing field of nutritional research. Many plants produce antioxidants that can slow the day-to-day damage inflicted by our environment. Active ingredients in traditional remedies, such as ginseng and echinacea, also show promise in alleviating illness and increasing overall health.

Dionex has developed a wide range of applications for analyzing ingredients in vitamin and herbal dietary supplements.

Vitamin B1, B2, B3, and B6 in Dietary Supplements

Thiamine (B1), riboflavin (B2), niacin (B3), and pyridoxine (B6) are water soluble vitamins that effect many important biological functions, including metabolism of carbohydrates, fats, and proteins, and maintenance of healthy muscle, skin, eyes, hair, and liver.

Vitamin D2 and D3

Vitamins D2 (cholecalciferol) and D3 (ergocalciferol) are two forms of an essential vitamin. They are used in fortified milk, dietary supplements, and various other foods.

Catechins and Caffeine in Green Tea Extracts

Catechins are flavonoid phytochemical compounds. They comprise up to 10% of the dry weight of some teas, especially green and white teas. They are considered to have strong antioxidant properties.

Boswellic Acids in Boswellia

Boswellia is a plant that contains triterpenoid compounds called boswellic acids. Boswellic acid and its derivatives have anti-carcinogenic, anti-tumor, and blood lipid lowering activities.

Silymarins in Milk Thistle

Silymarin is an antioxidant flavonoid complex derived from milk thistle (Silybum marianum). Silymarin has been shown to prevents toxins from penetrating the interior of liver cells, while promoting the growth of healthy new cells to repair liver damage. The main constituent of silymarin is silibinin.

Eleutherosides in Siberian Ginseng Extracts

Eluetherosides are glycosides with aromatic alcohol aglycones. They are found in Siberian Ginseng and they are considered to be responsible for the plants adaptogenic properties.

Kavalactones in Kava Kava Extracts

Kavalactones are the active ingredient in the roots of the Kava (or Kava Kava), a shrub commonly found on many of the Pacific Islands. It is considered to have muscle relaxant, anticovulsive, and anesthetic properties. Kava preparations are sold in the U.S. as capsules or teas.

Triterpene Glycosides in Black Cohosh Extracts

Black Cohosh is an herbal medication included in many dietary supplements designed for women who may help alleviate the symptoms of prementrual tension, menopause, or other gynocological problems.

Ginsenosides in American and Panax Ginseng Extracts

Ginsenosides are steroidal saponins which constitute the active ingredients in Ginseng. Their presence in extracts can be quantified as a measure of potency, using acetonitrile/water gradient with detection in the ultraviolet spectrum.

Phenolic Compounds in Echinacea Extracts

Herbalists consider Echinacea one of the best blood purifiers and an effective antibiotic. Constituents of Echinacea include polysaccharides, polyacetylenes, sesquiterpenes, polyphenols, and more.

Soy Isoflavones in Soy Extracts

These compounds represent a class of chemicals known as phytochemicals; natural compounds found in fruit and vegetables, they are neither vitamins, proteins, carbohydrates, nor minerals.

Extraction of Ginsenosides from Ginseng

Ginseng is an herbal medication derived from the root of the Panax genus of plants. It has been used for several thousands of years throughout the world and its purported medicinal properties are well documented.