October 2009, Sunnyvale, CA—Dionex Corporation has released a new applications notebook to help the pharmaceutical scientist by providing a wide range of application examples relevant to the pharmaceutical market.

The pharmaceutical industry is the largest consumer of HPLC instrumentation. In drug discovery, HPLC and IC systems are used both as stand-alone and front-end tools for mass spectrometers to screen drug candidates. In non-clinical development, the systems are used for analyzing in-vitro and in-vivo samples. In clinical trials, they are used to gather data on a potential drug’s safety and efficacy. The systems are also used in manufacturing for many tasks including QA/QC, and the validation of cleaning procedures. The wide range of applications presents a wide range of challenges to the analytical chemist.

The new Dionex Pharmaceutical Applications Notebook is designed to provide a wide variety of pharmaceutical- and biopharmaceutical-relevant examples in a convenient electronic format. HPLC, UHPLC and IC applications are divided into sections, which include Controlled Drugs, Over-the-Counter Medicines, Antibiotics, Anions/Cations/Organic Acids, and more. The Notebook also includes a detailed white paper covering the transfer of HPLC methods to UHPLC systems. There is also a HPLC/IC column selection guide to assist those involved in method development or chromatographers searching for equivalent replacement columns. At nearly 268 pages, the Dionex Pharmaceutical Applications Notebook contains a wealth of information that will be useful to any analytical laboratory.

Dionex (NASDAQ:DNEX) is a global leader in the manufacturing and marketing of liquid chromatography and extraction systems, consumables, and software for chemical analysis. The company's systems are used worldwide in environmental analysis and by the life sciences, chemical, petrochemical, food and beverage, power generation, and electronics industries. Our expertise in applications and instrumentation helps analytical scientists to evaluate and develop pharmaceuticals, establish environmental regulations, and produce better industrial products.