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Pharmaceutical / Biopharmaceutical Applications

Pharmaceutical / Biopharmaceutical IC and LC Application Notes
AN 289: Evaluation of the USP Risedronate Sodium Assay
AN 288: New HPLC and UHPLC Assay Methods for Tetracycline Hydrochloride and 4-Epianhydrotetracycline Hydrochloride Impurity in Tetracycline Drug Products
AN 284: Determination of Ethyl Sulfate Impurity in Indinavir Sulfate Drug Using Ion Chromatography
AN 283: Mass Spectrometry Compatible Separation of Itraconazole and Related Substances by UHPLC
AN: 269 Identification and Quantification at ppb Levels of Common Cations and Amines by IC-MS
AN: 267 Analysis of the Aminoglycoside Antibiotics Kanamycin and Amikacin Matches USP Requirements
AN 265: Quantification of Polyaromatic Hydrocarbons with a Boron-Doped Diamond Electrode
AN 262 Determination of 2-Ethylhexanoic Acid Impurity in Clavulanate
AN 259: Determination of N-Methylpyrrolidine in Cefepime with Nonsuppressed Conductivity Detection
AN 257: HPLC Assay Method for Drug Products Containing Anti-Tuberculosis Active Pharmaceutical Ingredients
AN 249:Determination of Methacholine Chloride and Potential Impurities Using a Reagent-Free Ion Chromatography System
AN 246: Determination of Ethylene Glycol and Diethylene Glycol in a Sorbitol Solution
AN 238: Determination of Sulfate and Sulfamate in Topiramate Using a Reagent-Free Ion Chromatography System
AN 237: Analysis of Benzalkonium Chloride on the Acclaim Surfactant Column by High-Performance Liquid Chromatography
AN 235: Determination of Oversulfated Chondroitin Sulfate and Dermatan Sulfate in Heparin Sodium Using Anion-Exchange Chromatography with UV Detection
AN 234: Simultaneous Determination of Pharmaceutical Peptides and Acetate by HPLC with UV Detection Using the Acclaim Mixed-Mode WAX-1 Column
AN 233: Determination of Galactosamine Containing Organic Impurities in Heparin by HPAE-PAD Using the CarboPac PA20 Column
AN 232: Determination of Anthraquinones and Stilbenes in Giant Knotweed Rhizome by HPLC with UV Detection
AN 228: Determination of Catecholamines in Human Plasma by Liquid Chromatography with Electrochemical Detection
AN 223: Determination of Ten Active Ingredients in Sunscreen-Containing Products in a Single Injection
AN 220: Determination of Inorganic Anion Impurities in a Water-Insoluble Pharmaceutical by Ion Chromatography with Suppressed Conductivity Detection
AN 215: Separation of Asparagine-Linked (N-Linked) Oligosaccharides from Human Polyclonal IgG Using the CarboPac PA200 Column
AN 214: Separation of Protein Phosphoisoforms Using Strong Anion-Exchange Chromatography
AN 211: Hydrophobic Interaction Chromatography for Separation of Tryptophan and Methionine Oxidized Peptides from Their Native Forms
AN 207: Chromatographic Fingerprinting of Flos Chrysanthema Indici Using HPLC
AN 205: Determination of Cefepime and Cefepime-Related Substances Using HPLC and UV Detection
AN 202: High Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection (HPAE-PAD) Analysis of Mannose-6-Phosphate
AN 199: Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography System
AN 195: Determination of Verapamil Hydrochloride Purity Using the Acclaim PA Column
AN 194: Determination of Carbachol In Ophthalmic Solutions Using a Reagent-Free Ion Chromatography System
AN 190: Determination of Sulfate Counter Ion and Anionic Impurities in Aminoglycoside Drug Substances by IC with Suppressed Conductivity Detection
AN 188: Determination of Glycols and Alcohols in Fermentation Broths Using Ion-Exclusion Chromatography and Pulsed Amperometric Detection
AN 186: Analysis of Paromomycin by HPAE-IPAD
AN 181: Determination of Streptomycin and Impurities Using HPAE-PAD
AN 180: Determination of Nevirapine Using HPLC with UV Detection
AN 164: Assay for Citrate and Phosphate in Pharmaceutical Formulations
AN 160: Determination of Residual Trifluoroacetate in Protein Purification Buffers and Peptide Preparations by Reagent-Free Ion Chromatography
AN 156: Determination of Anions in Toothpaste by Ion Chromatography
AN 148: Determination of Bethanechol by Ion Chromatography
AN 142: Determination of Tryptophan Using AAA-Direct
AN 132: Determination of Sulfur-Containing Antibiotics Using Integrated Pulsed Amperometric Detection (IPAD)
AN 130: Identification of a Hydroxylysine-Containing Peptide Using AAA-Direct
AN 129: Separation of Tryptophan and Methionine Oxidized Peptides from Their Unoxidized Forms
AN 128: Monitoring Stability of Monoclonal Antibodies by Cation-Exchange Chromatography
AN 127: Analysis of Monoclonal Antibody Heterogeneity by Cation-Exchange Chromatography: Separation of C-Terminal Lysine Variants
AN 125: Monitoring Protein Deamidation by Cation-Exchange Chromatography
AN 123: The Determination of Inorganic Anions and Organic Acids in Fermentation Broths
AN 122: The Determination of Carbohydrates, Alcohols, and Glycols in Fermentation Broths
AN 117: Quantification of Carbohydrates and Glycols in Pharmaceuticals
AN 116: Quantification of Anions in Pharmaceuticals
AN 115: Determination of Trifluoroacetic Acid (TFA) in Peptides
AN 106: Ion Chromatography in the Pharmaceutical Industry
AN 104: Analysis of Personal Care Products by Ion Chromatography
AN 70: Choline and Acetylcholine
AN 66: Determination of Neomycin B and Impurities Using HPAE-PAD
AN 61: Determination of Tobramycin and Impurities Using HPAE-PAD
Pharmaceutical / Biopharmaceutical IC and LC Application Briefs
AB 138: Separation of Cis and Trans Isomers of Crotamiton Using an Acclaim C30 Column
AB 136: Determination of Inorganic Counterions in Pharmaceutical Drugs Using Capillary IC
AB 126: Separation of Sinapine Thiocyanate in Semen Raphani Using an Acclaim Phenyl-1 Column
AB: 123 UHPLC Separation of Nine Corticosteroids in Under Four Minutes
AB 122: Separation of Etoposide Using an Acclaim Phenyl-1 Column
AB 119: Rapid Separation of Paclitaxel and Related Compounds in Palitaxel Injection
AB 116: Simultaneous Separation of Bisoprolol and Its Counterion Fumarate
AB 113: Fast Separation of Twelve Active Ingredients Used in Products Containing Sunscreen
AB 102: Determination of Aucubin, Genipoide, and Pinoresinol Diglucoside in Cortex Eucommiae Using ASE and HPLC
AB 101: High-Resolution Cation-Exchange Chromatography for Analysis of Protein Purity and Microheterogeneity
Pharmaceutical / Biopharmaceutical Customer Application Notes
CAN 101: Detection of Ethyl Glucuronide Using Pulsed Electrochemical Detection following Reversed-Phase High Performance Liquid Chromatography
CAN 107: Rapid His-Tag Purification of Recombinant Proteins Using Dionex ProPac IMAC Columns
Pharmaceutical / Biopharmaceutical Application Updates
AU 178: A Faster Solution with Increased Resolution for Determining Chromatographic Identity and Absence of OSCS in Heparin Sodium
AU 176: Preparation of Peptide N-Glycosidase F Digests for HPAE-PAD Analysis
AU 173: Enrichment and Identification of Chicken Ovalbumin and Phosphopeptides by Immobilized Metal Affinity and Reversed-Phase Chromatographies
AU 167: Determination of Tobramycin in Crude and In-Process Production Samples During Manufacturing Using HPAE-IPAD
AU 164: Determination of Glucosamine in Chondroitin Sulfate-Containing Dietary Supplements Using HPAE-PAD
AU 156: Evaluation of Acclaim HPLC Columns Using the National Institute of Standards Standard Reference Material 870
AU 152: An Improved Gradient Method for the AAA-Direct Separation of Amino Acids and Carbohydrates in Complex Sample Matrices
AU 141: Improved Long-Term Stability of N-Acetylneuraminic Acid and N-Glycolylneuraminic Acid Peak Area Responses Using Waveform A, a Quadruple Potential Waveform