Columns and Accessories > HPLC Columns > Specialty HPLC Columns > Acclaim Mixed-Mode HILIC-1 Columns
 
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Acclaim Mixed-Mode HILIC-1 Columns

Acclaim® Mixed-Mode HILIC-1 columns are packed with a new silica-based stationary phase that incorporates both reversed-phase (RP) and hydrophilic interaction liquid chromatography (HILIC) properties. The column features hydrophobic alkyl chain and hydrophilic diol functionalities.

The combined functionality of the new Acclaim Mixed-Mode HILIC-1 columns gives the chromatographer vastly more separation power then either reversed-phase or HILIC supports alone. This new Acclaim Mixed-Mode HILIC is designed to separate highly polar compounds and nonpolar molecules. It can be used in either reversed-phase mode or normal phase mode.

The Acclaim Mixed-Mode HILIC-1 column features:

  • Operation in both RP and HILIC modes
  • Retention of highly polar molecules unretained by RP columns
  • Unique selectivity complementary to RP columns
  • Superior performance compared to conventional diol-based columns

The Acclaim Mixed-Mode HILIC-1 is suitable for a broad range of applications, including drug metabolites, lipids, polyethylene glycols (PEGs), ethoxylated surfactants and more.

Acclaim Mixed-Mode HILIC-1 Columns  Specifications
Particle size: 5 µm
Base silica: Spherical, high-purity
Pore size: 120 Å
Surface area: 300 m2/g
Column chemistry: Proprietary alkyl diol
Order Information
Acclaim Mixed-Mode HILIC-1, 5 µm (4.6 x 150 mm)066843
Acclaim Mixed-Mode HILIC-1, 5µm (4.6 x 250 mm)066844
Acclaim Mixed-Mode HILIC-1, 5 µm (2.1 x 150 mm)066847
Acclaim Mixed-Mode HILIC-1 Guard, 5 µm (4.3 x 10 mm), Set of 2066845
Acclaim Mixed-Mode HILIC-1 Guard, 5 µm (2.1 x 10 mm), Set of 2066846
Guard Kit (Holder and Coupler)059526
SST Guard Cartridge Holder059456
Guard to Analytical Column Coupler059457
Data Sheets
Acclaim Mixed-Mode HILIC-1 Column Datasheet   489K
A New HILIC/RP Mixed-Mode Column and Its Applications in Surfactant Analysis    791K
Acclaim 120 Reversed-Phase Columns

The Acclaim® 120 columns are a highly characterized line of LC/MS compatible C18 and C8 phases that have very high surface coverage and very low metal content. These columns provide exceptional performance for a variety of applications in the pharmaceutical, nutraceutical, food, and life science separations areas.

Acclaim Library

A  selection of applications for Acclaim columns.

     
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