| | | | Integrated Flow Manager |
| The FLM-3000 Flow Manager series features UltiFlowTM active splitting technology, and integrates this with the thermostatted column oven. It also includes up to two low-dispersion 10-port valves, ready to use in automated sample preparation and multidimensional LC applications. The thermostatted column compartment, with a temperature range from 5–70 ºC, allows for the use of up to three columns. Use of the automated preheating/cooling option allows shorter warm-up/cool-down times, decreasing temperature stabilization times. - The Flow Manager is the ideal solution for chromatography users looking to work at nano/cap/micro flow rates and require high retention time precisions.
- Column compartment temperature range: 5–70 °C
- Column capacity of up to three microcolumns (max length: 30 cm)
- Integrated UltiFlow active flow splitting system
- Electronically controlled nano and capillary flow delivery
- Thermostatted for highly reproducible flow delivery
- Thermostatted 10-port microswitching valves for superior reproducibility and application flexibility
- Biocompatible option
UltiFlow Technology 
Reliable generation of nano and capillary gradients is achieved using the all-new, groundbreaking integrated active flow splitting system: UltiFlow technology (patent pending). UltiFlow technology significantly improves the gradient reproducibility and flow accuracy, compared to passive flow splitting approaches. Presplit gradient formation offers various advantages over splitless nanoflow gradients. Mixing is more homogeneous, gradient delays are minimized, and fast changes to the gradient profiles are optimized even under the lowest column flow rates. With UltiFlow, constant column flow is also preserved, working independent of solvent composition and column pressures. Even in case of partial column clogging from particulate in a sample, the programmed flow rate will be maintained. UltiFlow constantly monitors flow and immediately initiates corrective action for any deviations from the flow set-point. With the UltiMate TM 3000 and UltiFlow technology, reliable timing for peaks into the MS or fractions onto a MALDI plate is guaranteed—sample to sample, week to week, and instrument to instrument. 
| | | Integrated Flow Manager Specifications | | Temperature Range | 5–70 °C (max 15 °C below ambient) | | Temperature Accuracy | ± 0.5 °C | | Temperature Stability and Precision | ±0.1 °C | | Heatup/Cooldown Time | From 20 °C to 50 °C in less than 25 min;
From 50 °C to 20 °C in less than 35 min | | Switching Valves | Up to 2× 10-port low-dispersion microvalves | | Column Capacity | Three columns, max. 30-cm length | | Column Recognition | Electronic identification system for three columns | | Max. Column Pressure | 35 MPa (4900 psi) | | Flow Control | Nano, capillary, or micro thermostatted splitter cartridge with electronic splitter identification system | | Flow Range Selection | 50 nL/min to 1000 nL/min (using nano LC splitter) 0.5 µL/min to
10 µL/min (using capillary LC splitter), 10 µL/min to 200 µL/min
(using micro LC splitter) | | Wetted Parts | Fused silica, stainless steel (1.4571, 316 L), PEEK; Waste line:
PTFE, aluminum oxide (Al 2 O 3 ) | | Safety Features | Humidity sensor, gas sensor, and leak sensor | | Dimensions (h × w × d) | 19 × 42 × 51 cm (6.7 × 16.5 × 20 in.) | | Weight | 17 kg (37.4 lb) |
| | Order Information | | FLM-3100 Nano: UltiMate 3000 Nano Flow Manager with Two Integrated Motorized Switching Valves, 2x 2 Position, 10 Port | 5720.0010 | | FLM-3100 Cap: UltiMate 3000 Cap Flow Manager with Two Integrated Motorized Switching Valves, 2x 2 Position, 10 Port | 5720.0015 | | FLM-3100 Micro: UltiMate 3000 Micro Flow Manager with Two Integrated Motorized Switching Valves, 2x 2 Position, 10 Port | 5720.0018 | | FLM-3200 Nano: UltiMate 3000 Nano Flow Manager with Two Integrated Motorized Switching Valves, 1x 2 Position, 10 Port, 1x 2 Position-6 Port | 5720.0020 | | FLM-3200, CAP, 2X2P-10P Flow Manager with 2-Position 10-Port and 2-Position 6-Port Switching Valves
| 5720.0025 | | FLM-3200, MIC, 2X2P-10P Flow Manager with 2-Position 10-Port and 2-Position 6-Port Switching Valves
| 5720.0028 | | FLM-3300 Nano: UltiMate 3000 Nano Flow Manager with One Integrated Motorized Switching Valve, 1x 2 Position, 10 Port | 5720.0030 | | FLM-3300 Cap: UltiMate 3000 Cap Flow Manager with One Integrated Motorized Switching Valve, 1x 2 Position, 10 Port | 5720.0035 | | FLM-3300 Micro: UltiMate 3000 Micro Flow Manager with One Integrated Motorized Switching Valve, 1x 2 Position, 10 Port | 5720.0038 | | FLM-3100B Nano: UltiMate 3000 Nano Flow Manager with Two Integrated Motorized Switching Valves, 2x 2 Position, 10 Port, Biocompatible | 5721.0010 | | FLM-3100B, CAP, 2X2P-10P Biocompatible Flow Manager with Two 2-Position 10-Port Switching Valves
| 5721.0015 | | FLM-3100B, MIC, 2X2P-10P Biocompatible Flow Manager with Two 2-Position 10-Port Switching Valves
| 5721.0018 | | FLM-3200B Nano Flow Manager with Integrated 2-Position 10-Port and 2-Position 6-Port Switching Valves, Biocompatible
| 5721.0020 | | FLM-3200B, CAP, 2P-10P, 2P-6P Biocompatible Flow Manager with 2-Position 10-Port and 2-Position 6-Port Switching Valves
| 5721.0025 | | FLM-3200B, MIC, 2P-10P, 2P-6P Biocompatible Flow Manager with 2-Position 10-Port and 2-Position 6-Port Switching Valves
| 5721.0028 | | FLM-3300B Nano: UltiMate 3000 Nano Flow Manager with One Integrated Motorized Switching Valve, 1x 2 Position, 10 Port, Biocompatible | 5721.0030 | | FLM-3300B Cap: UltiMate 3000 Cap Flow Manager with One Integrated Motorized Switching Valve, 1x 2 Position, 10 Port, Biocompatible | 5721.0035 | | FLM-3300B, MIC, 1X2P-10P Biocompatible Flow Manager with 2-Position 10-Port Switching Valve
| 5721.0038 |
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|  |  | Modules | | | UltiMate ® 3000 LC modules achieve new levels of flexibility, performance, reliability, and ease of use. |
| LC and LC/MS Overview | Discover the UltiMate ® 3000 LCi series, and learn how LCi solutions can improve performance and productivity in your laboratory. |
| LCi Solutions |  | Find out how the UltiMate® 3000 LCi Series can provide you with LC solutions for your chromatographic challenges. |
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